Cao et al., Endocrinology 2004
(Acromegaly...) :
We also demonstrated that the constitutively active form of both p110, a subunit of PI3-K, and Akt inhibited activity of the human SR-BI/CLA-1 promoter
Yu et al., Hypertension 2007
:
Constitutively active Akt inhibits the activity of the hSR-BI/CLA-1 promoter, and a dominant negative mutant of Akt or mutagenesis of a FoxO1 response element in the hSR-BI/CLA-1 abolished the ability of Ang II to suppress promoter activity
Huang et al., J Lipid Res 2013
(Atherosclerosis) :
Our data suggest that MCP-1 impairs RCT activity in HepG2 cells by a PI3K/Akt mediated posttranslational regulation of ABCA1, ABCG1, and SR-BI cell-surface expression