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CXCR4 — MMP9

Text-mined interactions from Literome

Su et al., Zhonghua Yi Xue Za Zhi 2005 (Lung Neoplasms...) : The effect of CXCR4 expression on the cell migration, MMP-2 activity, adhesion and GRO-a expression of lung cancer cells were detected by chemotaxis and chemoinvasion assay, zymography, adhesion assay and RT-PCR respectively
Chinni et al., Prostate 2006 (Bone Neoplasms...) : CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells : the role of bone microenvironment associated CXCL12
Redondo-Muñoz et al., Blood 2006 (Leukemia, B-Cell...) : MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration
Yuecheng et al., Eur J Cancer Prev 2007 (Neoplasm Invasiveness...) : Moreover, SDF-1-CXCR4 interaction activated MMP-9 at the both transcription and protein levels and MMP-2 only at the post-translation level
Laird et al., Hum Reprod 2011 : Expression of CXCL12 and CXCR4 in human endometrium ; effects of CXCL12 on MMP production by human endometrial cells
Du et al., Hum Reprod 2012 : CsA up-regulated CXCL12 and CXCR4 expression in human first-trimester cytotrophoblast cells, but not in DSCs. Blocking the mitogen activated proteinkinase/extracellular signal regulated kinase ( MAPK/ERK1/2 ) signaling by U0126 abrogated the CsA induced increase in CXCL12 and CXCR4 expression and neutralizing antibodies to CXCL12 or CXCR4 completely inhibited the CsA induced increase in cell number, invasion and MMP-9 and MMP-2 activity of cytotrophoblast
Kawai et al., Cell Transplant 2012 (Disease Models, Animal...) : In vitro, we investigated the effect of MMP-9 on migration activity and CXCR4 expression on lineage negative ( Lin ( - ) ) BM cells