Gene interactions and pathways from curated databases and text-mining

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GRAP2 — IGF1

Text-mined interactions from Literome

Celil et al., J Biol Chem 2005 : An important role for bone morphogenetic protein-2 (BMP-2) and insulin-like growth factor-I (IGF-I) on Osx expression and the requirement for p38 for the BMP-2 mediated effect was reported previously by our group
Zhang et al., Breast Cancer Res Treat 2005 (Breast Neoplasms) : The mitogen activated protein kinase ( MAPK ), p38, was also activated by IGF-I and inhibition of p38 by SB203580 blocked IGF-I induced cell motility
Ren et al., Proc Natl Acad Sci U S A 2010 (MAP Kinase Signaling System) : Hypoxia suppresses basal and IGF induced Akt-mTOR and p38 activity, whereas it enhances and prolongs IGF induced Erk1/2 activation in a HIF-1 dependent fashion
Seto-Young et al., Horm Metab Res 2011 (MAP Kinase Signaling System) : Differential roles of MAPK-Erk1/2 and MAPK-p38 in insulin or insulin-like growth factor-I (IGF-I) signaling pathways for progesterone production in human ovarian cells
Guan et al., Am J Physiol 1998 : Our data also indicate that both insulin and IGF-I enhance IL-1 beta induced p38 mitogen activated protein kinase ( MAPK ) phosphorylation and SAPK activation