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ESAT — NFKB1
Text-mined interactions from Literome
Pathak et al., Nat Immunol 2007
:
Here we show that
ESAT-6 inhibited activation of transcription factor
NF-kappaB and interferon-regulatory factors ( IRFs ) after Toll-like receptor ( TLR ) signaling ; inhibition of TLR signaling by ESAT-6 required the kinase Akt
Ganguly et al., Immunol Cell Biol 2008
(Tuberculosis) :
Mycobacterium tuberculosis secretory proteins CFP-10, ESAT-6 and the CFP10 :
ESAT6 complex inhibit lipopolysaccharide
induced NF-kappaB transactivation by downregulation of reactive oxidative species ( ROS ) production