Gene interactions and pathways from curated databases and text-mining

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SP4 — TNF

Text-mined interactions from Literome

Nair et al., Cell Immunol 1995 : Separated mononuclear cells also produced significant levels of TNF in response to SP and SP 4-11 ... Anti-TNF-alpha antibodies neutralized the TNF induced by SP 4-11 in plasma
Ho et al., J Neuroimmunol 1998 : We have investigated the effects of the substance P C-terminal octapeptide analogues [ Pro4, Glu ( OBzl ) 11 ] SP4-11 , [ Hyp4, Glu ( OBzl ) 11 ] SP4-11, [ cHyp4, Glu ( OBzl ) 11 ] SP4-11 and [ kPro4, Glu ( OBzl ) 11 ] SP4-11 on the constitutive and/or lipopolysaccharide (LPS) induced expression of tumor necrosis factor ( TNF-alpha ) in both freshly isolated human blood monocytes ( FIBM ) and monocyte derived macrophages ( MDM )