◀ Back to CD4
CD4 — PIK3R1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Phu et al., J Leukoc Biol 2001
:
PI3-K inhibition
resulted in a modest decrease in anti-CD3 induced
CD4 ( + ) T-cell proliferation but failed to affect IL-2 expression by anti-CD3 activated CD4 ( + ) T cells
Trucy et al., Cell Immunol 2006
:
CD4 binding also
increases interactions between
PI3K and activated PKCzeta and PDK1
Gamper et al., Frontiers in immunology 2012
:
In this review, we focus on how
PI3K activation
directs mature
CD4 T cell activation and effector function by pathways dependent on and independent of mTOR signaling