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PDCD2 — TNF
Text-mined interactions from Literome
Pryhuber et al., Am J Respir Cell Mol Biol 2000
(Pneumonia) :
Tumor necrosis factor (TNF) receptor ( TNFR ) -associated factors 1 and 2 ( TRAF1 and TRAF2 ) and inhibitor of apoptosis proteins cIAP1 ( MIHB ) and cIAP2 ( MIHC ) were recently identified as proteins that associate with the TNF-alpha receptors TNFRI ( p55 ) and TNFRII ( p75 ) and inhibit
TNF-alpha induced
programmed cell death or apoptosis
Arrigo et al., Pathol Biol (Paris) 2000
(Neoplasms) :
These proteins are also known to interfere with
programmed cell death induced by
TNF alpha and Fas ligand
Robichaud et al., AIDS Res Hum Retroviruses 2000
:
Since ceramide is an important regulatory molecule of
programmed cell death induced by
TNF-alpha , we examined whether nef could alter TNF-alpha induced apoptosis in the U251MG human astrocytoma cell line
Ivanov et al., Oncogene 2001
(Melanoma) :
Our finding identifies p38,
TNFalpha and NF-kappaB among key players that efficiently sensitizes melanoma cells to UV-, ribotoxic ( anisomycin ) and radiomimetic chemicals
induced programmed cell death in response to aberrant TRAF2 signaling
Tang et al., Nature 2001
:
The proinflammatory cytokine
tumour necrosis factor-alpha (TNF-alpha) regulates immune responses, inflammation and
programmed cell death ( apoptosis )
Huber et al., Digestion 2002
:
The aim of our current study was to identify the
effect of
TNF-alpha on
programmed cell death
Cusson et al., J Exp Med 2002
:
Fas and the
tumor necrosis factor receptor (TNFR)1 regulate the
programmed cell death of lymphocytes
Tang et al., Mol Cell Biol 2002
(MAP Kinase Signaling System) :
The proinflammatory cytokine
tumor necrosis factor alpha (TNF-alpha) regulates immune responses, inflammation, and
programmed cell death ( apoptosis )
Bezzi et al., J Biol Chem 2003
:
Zoledronate sensitizes endothelial cells to
tumor necrosis factor induced
programmed cell death : evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt ... Taken together these data demonstrate that zoledronate sensitizes endothelial cells to
TNF induced , caspase independent
programmed cell death and point to the FAK-PKB/Akt pathway as a novel zoledronate target
Dinarello et al., Clin Exp Rheumatol 2002
(Autoimmune Diseases) :
IL-1 is distinct from tumor necrosis factor (TNF) ; IL-1 and TNFalpha share several biological properties but the salient difference is that
TNF receptor signaling
induces programmed cell death whereas IL-1 receptor signaling does not
Weitsman et al., J Steroid Biochem Mol Biol 2004
(Breast Neoplasms) :
Activation of p38 MAP kinase was shown to have both pro- and anti-apoptotic actions in
TNF-alpha induced
programmed cell death depending on cell context
Lecour et al., Cardiovasc Res 2005
(Myocardial Ischemia...) :
Tumor Necrosis Factor alpha (TNF alpha) induces
programmed cell death and contributes to cardiac ischemia/reperfusion injury
Pajak et al., J Physiol Pharmacol 2005
(Colorectal Neoplasms) :
Apparently, cycloheximide sensitized cells to
TNF-alpha induced
programmed cell death
Lange et al., Biochem Biophys Res Commun 2005
:
The apoptosis inhibitory domain of FE65-like protein 1 regulates both apoptotic and caspase independent
programmed cell death mediated by
tumor necrosis factor
Varfolomeev et al., J Biol Chem 2005
:
Apo2
ligand/tumor necrosis factor (TNF) related apoptosis inducing ligand ( Apo2L/TRAIL ) mainly
activates programmed cell death through caspases
Zhang et al., Chin Med J (Engl) 2007
(Carcinoma, Adenoid Cystic...) :
A20, also known as tumor necrosis factor alpha induced protein 3 ( TNFaip3 ), is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B (NF-kappaB) activity and prevents
tumor necrosis factor (TNF) mediated
programmed cell death
Wei et al., BMC biotechnology 2008
:
A20 is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B activity and
tumor necrosis factor (TNF) mediated
programmed cell death
Chen et al., Hum Immunol 2008
:
Overexpression of the
PDCD2-like gene
results in inhibited
TNF-alpha production in activated Daudi cells ... Overexpression of
PDCD2-like gene effectively
attenuated tumor necrosis factor (TNF)-alpha release but elevated interleukin (IL)-6 and PDCD2 expression induced by lipopolysaccharide (LPS)
Oshima et al., Nature 2009
:
ABIN-1 deficient cells are hypersensitive to
tumour necrosis factor (TNF) induced
programmed cell death , and TNF deficiency rescues ABIN-1 deficient embryos
Seixas et al., Proc Natl Acad Sci U S A 2009
(Liver Failure...) :
Expression of HO-1 suppresses the pro-oxidant effects of free heme, preventing it from sensitizing hepatocytes to undergo
TNF mediated
programmed cell death by apoptosis
Mangan et al., J Immunol 1991
:
Lipopolysaccharide,
tumor necrosis factor-alpha , and IL-1 beta
prevent programmed cell death ( apoptosis ) in human peripheral blood monocytes
Tavares et al., Immunity 2010
:
A20 is a ubiquitin modifying enzyme that restricts NF-kappaB signals and protects cells against
tumor necrosis factor (TNF) induced
programmed cell death
Guan et al., Biomaterials 2010
:
It is thus suggested that the co-immobilized TNF-a plus IFN-? promotes the activation of some unknown key markers in response to IFN-?, and the binding of the co-immobilized
TNF-a plus IFN-? with some other TNF-a receptors
results in enhanced
programmed cell death in HeLa cells
Eissner et al., Blood 1995
:
Critical
involvement of transmembrane
tumor necrosis factor-alpha in endothelial
programmed cell death mediated by ionizing radiation and bacterial endotoxin
Tabibzadeh et al., Hum Reprod 1995
:
It has been suggested that tumour necrosis factor
(TNF) alpha secreted during the secretory/menstrual phases
plays a role in induction of
programmed cell death in these cells
Selleri et al., J Cell Physiol 1995
:
Interferon-gamma and
tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and
induce programmed cell death
Ayala et al., Shock 1995
(Sepsis) :
The induction of accelerated thymic
programmed cell death during polymicrobial sepsis :
control by corticosteroids but not
tumor necrosis factor
Baier-Bitterlich et al., FEBS Lett 1995
:
Effect of neopterin and 7,8-dihydroneopterin on
tumor necrosis factor-alpha induced
programmed cell death
Gotlieb et al., Am J Obstet Gynecol 1994
(Ovarian Neoplasms) :
Induction of
programmed cell death ( apoptosis ) by
tumor necrosis factor-alpha was quantitated by means of a deoxyribonucleic acid fragmentation assay
Briskin et al., Arch Otolaryngol Head Neck Surg 1996
(Carcinoma, Squamous Cell...) :
Specifically, to find out whether
TNF-alpha induces apoptotic (
programmed ) cell death
Cuvillier et al., Nature 1996
:
Ceramide is an important regulatory participant of
programmed cell death ( apoptosis )
induced by
tumour-necrosis factor (TNF)-alpha and Fas ligand, members of the TNF superfamily
Deiss et al., EMBO J 1996
:
Cathepsin D protease mediates
programmed cell death induced by interferon-gamma, Fas/APO-1 and
TNF-alpha
Sytwu et al., Immunity 1996
(Lymphoproliferative Disorders) :
The
roles of Fas/APO-1 ( CD95 ) and
TNF in antigen induced
programmed cell death in T cell receptor transgenic mice
Watson et al., Shock 1996
(Inflammation) :
Bacterial ingestion,
tumor necrosis factor-alpha , and heat
induce programmed cell death in activated neutrophils ... The results demonstrate, for the first time, that the mechanisms by which LPS delays PMN apoptosis are overridden by the mechanisms by which
TNF-alpha , E. coli ingestion, and heat shock
induce programmed cell death
Shu et al., Proc Natl Acad Sci U S A 1996
:
The association of TRADD, a 34-kDa cytoplasmic protein containing a C-terminal death domain, with aggregated
TNF receptor 1 (TNF-R1) through their respective death domains
leads to NF-kappa B activation and
programmed cell death
Schubert et al., Ann N Y Acad Sci 1997
:
Adenosine agonists also depressed the release of the potentially toxic cytokine
TNF alpha and
induced programmed cell death in immunologically activated microglial cells
Tollefson et al., Nature 1998
:
In adenovirus infected cells,
programmed cell death ( apoptosis )
induced by the cytokine
tumour necrosis factor (TNF) is inhibited by several adenovirus encoded proteins
Wuttke et al., J Reprod Fertil Suppl 1997
:
Furthermore,
TNF alpha
stimulates programmed cell death ( apoptosis ) in luteal cells kept under culture conditions
Wang et al., Nat Genet 1998
(Leukemia, Promyelocytic, Acute) :
We also found that Pml is essential for
induction of
programmed cell death by Fas,
tumour necrosis factor alpha (TNF) , ceramide and type I and II interferons ( IFNs )