Gene interactions and pathways from curated databases and text-mining

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CGA — PRL

Text-mined interactions from Literome

Duval et al., Psychoneuroendocrinology 1999 : Thyrotropin ( TSH ) response to 0800 and 2300 h protirelin ( TRH ) challenges, and adrenocorticotropic hormone ( ACTH ), cortisol, and prolactin (PRL) responses to D-fenfluramine ( D-FEN ), a specific 5-HT releasing/uptake inhibiting agent, were examined in 60 drug-free DSM-IV major depressed inpatients and 20 hospitalized controls
Wersinger et al., Endocrine 1999 : Gonadotropin subunit and PRL mRNA responses to E2 treatment ( both inhibitory and stimulatory ) were absent in ERalphaKO mice, suggesting a critical role for ERalpha
Kanasaki et al., Biol Reprod 2002 : Thyrotropin releasing hormone (TRH) rapidly stimulated the secretion of both prolactin and growth hormone from GH3 cells
, Res Reprod 1977 : Thyrotropin releasing hormone (TRH) is responsible for the pituitary release of prolactin and growth hormone (GH) in adult rats, though GH will release more prolactin than TRH in neonatal rats
Haug et al., Acta Physiol Scand 2004 : Thyrotropin releasing hormone (TRH) induces biphasic changes in the electrical activity, the cytosolic free Ca2+ concentration ([Ca2+]i), and prolactin secretion from both GH cells and native lactotrophs
Mørk et al., Acta Physiol Scand 2005 : Thyrotropin releasing hormone (TRH) induces biphasic changes in electrical activity, cytosolic free Ca ( 2+ ) level ( [ Ca ( 2+ ) ] ( i ) ), and prolactin secretion from both clonal GH cells and native lactotrophs
Roti et al., Acta Endocrinol (Copenh) 1990 : Thyrotropin releasing hormone does not stimulate prolactin release in the preterm human fetus
Ramsdell et al., J Cell Physiol 1989 : Thyrotropin releasing hormone (TRH) and epidermal growth factor both enhance prolactin synthesis and substrate adhesion ( a morphological change called stretching ) of GH4 rat pituitary cells
Aub et al., J Biol Chem 1986 (Pituitary Neoplasms) : Thyrotropin releasing hormone (TRH) stimulated a rapid rise in inositol trisphosphate ( IP3 ) formation and prolactin release from 7315c tumor cells
Ozawa et al., Am J Physiol 1982 (Pituitary Neoplasms) : Thyrotropin releasing hormone (TRH) , Ba2+, and high concentration of K+ enhance the release of prolactin from GH3 cells
Login et al., Brain Res 1983 : Thyrotropin releasing hormone (TRH) , but not dibutyryl cyclic AMP ( dbcAMP ), the calcium ionophore A23187 or excess Ca2+, stimulated both [ 3H ] Prl and Prl secretion in the presence of reserpine
Brostrom et al., J Cell Physiol 1984 (Pituitary Neoplasms) : Thyrotropin releasing hormone (TRH) rapidly enhanced amino acid incorporation and prolactin production, with both effects being reserved by EGTA in excess of extracellular Ca2+ or prevented by cellular Ca2+ depletion
Richards et al., Neuroendocrinology 1980 : Thyrotropin releasing hormone (TRH) increased plasma prolactin in male and female trained conscious dogs
Moriarty et al., Am J Physiol 1981 (Pituitary Neoplasms) : Thyrotropin releasing hormone (TRH) also stimulated PRL release but had no effect on cellular calcium accumulation