Gene interactions and pathways from curated databases and text-mining

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GNRH1 — GRAP2

Text-mined interactions from Literome

Liu et al., Mol Endocrinol 2002 : In this paper, we demonstrate that GnRH activates ERK, c-Jun N-terminal kinase, and p38MAPK in the LbetaT2 gonadotrope cell line
Bonfil et al., Endocrinology 2004 : Extracellular signal regulated kinase, Jun N-terminal kinase, p38 , and c-Src are involved in gonadotropin releasing hormone stimulated activity of the glycoprotein hormone follicle stimulating hormone beta-subunit promoter ... Thus, PKC, ERK, JNK, p38 , and c-Src, but not Ca ( 2+ ), are involved in GnRH induction of the ovine FSHbeta gene
White et al., Mol Endocrinol 2008 (MAP Kinase Signaling System) : In contrast to Galpha ( i ) or chimeric Galpha ( qi5 ), transfection of Galpha ( q ) cDNA enabled GnRH to induce phosphorylation of ERK, jun-N-terminal kinase, and P38
Sviridonov et al., Mol Cell Endocrinol 2013 (MAP Kinase Signaling System...) : Sustained activation of p38 was observed for PMA and A23187 in Du-145 cells, while p38 activation by GnRH , PMA and A23187 in LßT2 cells was transient