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MLST8 — PLD6
Text-mined interactions from Literome
Yoon et al., J Cell Sci 2008
:
Instead,
PLD1 positively
regulates mTOR signaling leading to the production of IGF2, an autocrine factor instrumental for the initiation of satellite cell differentiation
Suryawan et al., J Appl Physiol 2010
:
Our results suggest that the enhanced activation of
mTORC1 in muscle of neonatal pigs is in part
due to regulation by PRAS40,
PLD1 , and the Rag GTPases
Arous et al., Diabetologia 2011
:
Oleate mediated
mTORC1 activation
required phospholipase D activation, which produces phosphatidic acid and is known to render mTORC1 rapamycin resistant
Razmara et al., Cell communication and signaling : CCS 2013
:
In addition, PDGF-BB induced activation of
mTORC1 , as measured by phosphorylation of the downstream S6 protein, was
dependent on
phospholipase D ( PLD ) ...
mTORC1 is activated in a
PLD dependent manner and promotes phosphorylation of the S6 protein, whereas mTORC2, in concert with PLC? signaling, promotes Akt phosphorylation