Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
TNS1
→
PTK2
(decreases, TNS1 Activity)
Evidence: The sentence (ResnetDB) Moreover, treatment of wild-type cells with tyrphostin AG1007, which inhibits both pp60(c-src) and FAK activity, induced accumulation of tensin in peripheral focal adhesions. is translated to Activation of TNS (Homo sapiens) Gene Expression by PTK2 (Homo sapiens) Protein The following edits have been made already none Links Doc Sourcerer for 11493667 TNS (Homo sapiens) Gene Expression PTK2 (Homo sapiens) Protein
BioCarta erk and pi-3 kinase are necessary for collagen binding in corneal epithelia:
ECM/Integrin-alpha/Integrin-betaTalin/Calpain1/actin (active1)/p130cas/FAK/CSK/Paxillin/Vinculin/alp complex (ITGA1-PTK2-BCAR1-ACTN3_ACTN2_ACTN1_ACTN4-ZYX-TLN1-ITGB1-VCL-PXN-CSK-ACTA1-TNS1-CAPN1)
→
ECM/Integrin-alpha/Integrin-betaTalin/Calpain1/actin/p130cas/FAK/CSK/Paxillin/Vinculin/alpha-actinin complex (ACTA1-VCL-ITGB1-ZYX-TNS1-CSK-CAPN1-ITGA1-ACTN3_ACTN2_ACTN1_ACTN4-PTK2-BCAR1-TLN1-PXN)
(actin filament polymerization, collaborate)
BioCarta erk and pi-3 kinase are necessary for collagen binding in corneal epithelia:
ECM/Integrin-alpha/Integrin-betaTalin/Calpain1/actin/p130cas/FAK/CSK/Paxillin/Vinculin/alpha-actinin complex (ACTA1-VCL-ITGB1-ZYX-TNS1-CSK-CAPN1-ITGA1-ACTN3_ACTN2_ACTN1_ACTN4-PTK2-BCAR1-TLN1-PXN)
→
PIP2/Gelsolin complex (GSN)
(actin filament polymerization, collaborate)