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PTK2 — PTPRC
Text-mined interactions from Literome
Yu et al., Clin Exp Immunol 2002
:
However, only
anti-CD45RO suppressed Src family
protein tyrosine kinase p56lck expression in the cells
He et al., Eur J Immunol 2002
(Calcium Signaling) :
CD45 , a transmembrane protein tyrosine phosphatase (PTP), can either positively or negatively
regulate Src-family
protein tyrosine kinase ( PTK ) activity in vivo
Koretzky et al., J Immunol 1992
(Second Messenger Systems) :
These results support the
role of
CD45 tyrosine phosphatase activity in regulating the TCR activated
PTK
Dawes et al., J Med Genet 2006
(Hepatitis C) :
C77G individuals showed an increased proportion of primed
CD45RA and effector memory CD8 T cells and more rapid
activation of the lymphocyte specific
protein tyrosine kinase ( Lck ) following CD3 stimulation
Koretzky et al., J Biol Chem 1993
:
These data suggest strongly that lck is the relevant protein tyrosine kinase found in CD45 immunoprecipitates in the Jurkat T cell line and that there is an additional association between
CD45 and p34 which does not
require the presence of the
protein tyrosine kinase
Péléraux et al., Virology 1998
:
Our data show that cells respond to 13B8.2 postinfection treatment regardless of CD45 expression, indicating that neither CD45 nor
PTK regulated by
CD45 are implicated in the mechanism of action of this antibody