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ITGA6 — PTK2

Pathways - manually collected, often from reviews:

• KEGG Regulation of actin cytoskeleton: ITGA1/ITGA10/ITGA11/ITGA2/ITGA2B/ITGA3/ITGA4/ITGA5/ITGA6/ITGA7/ITGA8/ITGA9/ITGAD/ITGAE/ITGAL/ITGAM/ITGAV/ITGAX/ITGB1/ITGB2/ITGB3/ITGB4/ITGB5/ITGB6/ITGB7/ITGB8 → Complex of BCAR1-CRK-CRKL-PTK2 (protein-protein, activation)
  
• KEGG Pathways in cancer: Complex of ITGA2-ITGA2B-ITGA3-ITGA6-ITGAV-ITGB1 → PTK2 (protein-protein, activation)
• KEGG Small cell lung cancer: Complex of ITGA2-ITGA2B-ITGA3-ITGA6-ITGAV-ITGB1 → PTK2 (protein-protein, activation)
• NCI Pathway Database CXCR4-mediated signaling events: alpha-beta1 Integrin (ITGA8/ITGB1/ITGA10/ITGB1/ITGA6/ITGB1/ITGA1/ITGB1/ITGA3/ITGB1/ITGA2/ITGB1/ITGAV/ITGB1/ITGA11/ITGB1/ITGA4/ITGB1/ITGA7/ITGB1/ITGA5/ITGB1/ITGA9/ITGB1) → FAK/p130 Cas/Paxillin complex (PTK2-BCAR1-PXN) (cell adhesion, collaborate)
  Okabe et al., J Hematother Stem Cell Res 2002, Glodek et al., Leukemia 2007
  Evidence: mutant phenotype, assay