Gene interactions and pathways from curated databases and text-mining

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SUMO1 — TCF4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Ihara et al., Mol Cell Biol 2005 : Conjugation of SUMO-1 to the amino terminus of PIASy ( K35R ) neither enhanced sumoylation of Tcf-4 nor stimulated the transcriptional activity of Tcf-4
Yang et al., EMBO J 2005 : Our data therefore reveal a novel coactivator function for PIASx ( alpha ) through reversing SUMO mediated repression of transcription factor activity