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ACKR3 — CXCR4

Pathways - manually collected, often from reviews:

• Reactome Reaction: ACKR3 → CXCR4 (reaction) Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Text-mined interactions from Literome

Wang et al., J Biol Chem 2008 (Neoplasm Metastasis...) : In addition, it was observed that CXCR7/RDC1 levels are regulated by CXCR4
Melchionna et al., Muscle Nerve 2010 : Western blot analysis and real-time polymerase chain reaction ( PCR ) were performed to evaluate in vitro the effect of SDF-1 and CXCR4 and CXCR7 inhibition on myogenic differentiation
Sánchez-Alcañiz et al., Neuron 2011 : Thus, Cxcr7 is necessary to regulate Cxcr4 protein levels, thereby adapting chemokine responsiveness in migrating cells
Haege et al., PloS one 2012 : CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney
Uto-Konomi et al., Biochem Biophys Res Commun 2013 : We show that ß-arrestin recruitment to CXCR4 is reduced by over-expression of CXCR7 and activation of CXCR7 by agonist treatment reduces the protein level of CXCR4
Ma et al., J Biol Chem 2013 (Atherosclerosis...) : Furthermore, CXCR7 activation increased macrophage phagocytic activity, which was suppressed by CXCR7 siRNA silencing or by inhibiting either the JNK or p38 pathways, but was not affected by blocking CXCR4