◀ Back to TNF

MPO — TNF

Text-mined interactions from Literome

Hachiya et al., Biochim Biophys Acta 2000 : Role of TNFalpha in regulation of myeloperoxidase expression in irradiated HL60 promyelocytic cells
Altavilla et al., Life Sci 2000 (Coronary Disease...) : Myocardial ischaemia plus reperfusion in untreated rats produced marked myocardial necrosis, increased serum CPK activity ( 196.5 +/- 19 U/100 ml, at the end of reperfusion ) and myeloperoxidase activity ( MPO, a marker of leukocyte accumulation ) both in the area-at-risk ( 4.5 +/- 0.5 U/g/tissue ) and in necrotic area ( 8.2 +/- 1.2 U/g/tissue ), reduced myocardial contractility ( 1,706 +/- 52 mmHg/s, at the end of reperfusion ) and induced a marked increase in the serum levels of TNF-alpha ( 1,950 +/- 97 pg/ml, at 1 h of reperfusion ) and IL-6 ( 998 +/- 16 U/ml, at the end of reperfusion )
Leung et al., J Immunol 2001 (Arthritis, Rheumatoid...) : The latter was accompanied by reduction in tissue myeloperoxidase expression and suppressed local TNF-alpha production
Lefkowitz et al., Immunol Cell Biol 2001 (Arthritis, Rheumatoid...) : Several years ago the present investigators reported that binding of inactive myeloperoxidase ( iMPO ) to the macrophage-mannose receptor resulted in the induction of TNF and other cytokines
Tian et al., World J Gastroenterol 2003 (Colitis, Ulcerative) : After EA at ST36, m ( C ) /m ( B ) and MPO activity were reduced significantly ( 5.3+/-2.0 vs 8.5+/-2.6 ; 104+/-36 vs 145+/-25, P < 0.01, 0.05 ) compared with those of UC control group. Serum TNF-alpha and colonic TNF-alpha mRNA level were inhibited by EA stimulation at ST36 ( P < 0.01 ). The inhibitory rate was 16 % and 44 %, respectively. Morphologic damage score was also increased markedly in rat with UC ( P < 0.01 ), whereas it was decreased by EA at ST36 ( P < 0.05 ). There was no significant difference between UC control group and UC+EA at non-acupoint ( P > 0.05 )
Vij et al., Invest Ophthalmol Vis Sci 2005 (Keratitis) : Lum-/- -wounded corneas showed delayed healing, reduced recruitment of macrophages and neutrophils, lower MPO levels, and no induction of the proinflammatory cytokines TNFalpha and IL1beta
Yumura et al., Microbiol Immunol 2006 (Disease Models, Animal...) : MPO-ANCA increased slightly at 4 and markedly at 9 weeks, and the TNF-alpha level increased at 11 weeks
Hsieh et al., Clin Rheumatol 2007 : The spontaneous membrane expression of MPO and PR3 on PMN could be significantly increased by lipopolysaccharide (LPS) and TNF-alpha , but not by IL-8 or GRO-alpha
Qian et al., Am J Chin Med 2006 (Acute Disease...) : Shen-Fu ( 10,100 mg/kg ) decreased MPO activity and wet/dry weight ratio and inhibited TNF-alpha and IL-6 production, endotoxin induced NF-kappa B activation
Srivastava et al., J Immunol 1991 : We investigated the stability of LF and MPO mRNA and the effects of purified recombinant human TNF-alpha on LF and MPO levels in normal human bone marrow
Lee et al., J Ethnopharmacol 2009 (Acute Disease...) : Production of pro-inflammatory cytokines ( tumor necrosis factor (TNF)-alpha , interleukin (IL)-1beta ), activation of myeloperoxidase , and histological assessment were examined in acute and chronic skin inflammation using 12-O-tetradecanoyl-phorbol-13-acetate ( TPA ) -induced mouse ear edema
Lee et al., Inflammation 2009 (Colitis) : The TNBS treatment caused colon shortening, increased myeloperoxidase activity, induced IL-1beta, TNF-alpha , and IL-6 expression in the colon, activated NF-kappaB, and potentiated the GAG degrading activities of intestinal microflora
Lee et al., J Ethnopharmacol 2009 (Acute Disease...) : Production of pro-inflammatory cytokines ( TNF-alpha and IL-1 beta ), activation of myeloperoxidase , and histological assessment were examined in acute and chronic skin inflammation using 12-O-tetradecanoyl-phorbol-13-acetate ( TPA ) -induced mouse ear edema
Boussetta et al., PloS one 2009 (Colitis) : Punicic acid also inhibited fMLP- and TNFalpha+fMLP induced MPO extracellular release from neutrophils
Wang et al., Transplant Proc 2010 (Brain Death...) : Biliverdin reversed the aggravation of Pa ( O ( 2 ) ) in recipients, reduced the grafts wet/dry ratio, decreased the severity of lung injury measured by histologic examination, reduced serum tumor necrosis factor-alpha and interleukin-8 levels and inhibited myeloperoxidase activity (MPO) in the grafts
Liu et al., J Ethnopharmacol 2011 (Colitis) : IG significantly ameliorated macroscopic damage and histological changes, reduced the activity of MPO , depressed MDA and NO levels and effectively inhibited the protein and mRNA expressions of NF-?Bp65, TNF-a and IL-6 in the colon tissues of experimental colitis in a dose dependent manner
Mouzaoui et al., Int Immunopharmacol 2012 (Colitis) : TNF-a-toxicity led to significant increase in myeloperoxidase ( MPO, an index of neutrophils infiltration ), nitrites ( stable nitric oxide metabolites ) and malondialdehyde ( MDA, a marker of lipid peroxides ) levels and cell apoptosis in liver and colon
Oberyszyn et al., Mol Carcinog 1998 (Inflammation...) : Reverse transcription-polymerase chain reaction and immunohistochemical techniques were used to demonstrate that 24 h to 1 wk after UVB-light irradiation, PTX inhibited UVB induced TNF-alpha gene expression, inhibited the increase in epidermal TNF-alpha protein synthesis, blocked the increase in epidermal proliferation observed after exposure to UVB light, and decreased production of myeloperoxidase by neutrophils infiltrating into the dermis
Squadrito et al., Eur J Pharmacol 1999 (Disease Models, Animal...) : Myocardial ischaemia plus reperfusion in untreated rats produced marked myocardial necrosis, increased serum CPK activity and myeloperoxidase activity ( a marker of leukocyte accumulation ) both in the area-at-risk and in the necrotic area, reduced myocardial contractility and induced a marked increase in the serum levels of the TNF-alpha