Gene interactions and pathways from curated databases and text-mining

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FCGR2B — TNF

Text-mined interactions from Literome

Samsom et al., J Immunol 2005 : In vitro it was shown that absence of FcgammaRIIB under tolerogenic conditions led to increased IgG induced release of inflammatory cytokines such as MCP-1, TNF-alpha , and IL-6 by bone marrow derived DC, and increased their expression of costimulatory molecules, resulting in an altered immunogenic T cell response associated with increased IL-2 and IFN-gamma secretion
Monari et al., J Immunol 2006 : The FcgammaRIIB blockade inhibits GXM induced IL-10 production and induces TNF-alpha secretion
Zhang et al., Vet Microbiol 2012 : In this study, our results indicated that selective activation of porcine Fc?RIIB in PAM cells up-regulated significantly mRNA levels of IFN-a and TNF-a at any time point post-pretreatment, suggesting that porcine Fc?RIIB signal can enhance the innate antiviral response of host cells
Knowles et al., Am J Physiol 1997 (Anoxia) : During reoxygenation, both whole blood PMN phagocytosis and bactericidal activity were reduced in the presence of IL-8, TNF-alpha , or IL-1beta, and in subsets of PMN with reduced phagocytosis H/R reduced CD64, CD32w , CD16, CD35, and CD11b/CD18 expression in the presence of each cytokine