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SOD2 — TP53

Text-mined interactions from Literome

Hussain et al., Cancer Res 2004 : Microarray expression analysis of doxorubicin exposed, related human lymphoblasts, p53 wild-type ( WT ) Tk6, and p53 mutant WTK1 identified the p53 dependent up-regulation of manganese superoxide dismutase ( MnSOD ) and glutathione peroxidase 1 (GPx)
Doonan et al., J Neurochem 2009 : Furthermore, inhibition of p53 partially blocks the observed increase in SOD-2 and sestrin-1 expression indicating that p53 expression is upstream of both antioxidants
Dhar et al., J Biol Chem 2010 : Nuclear factor kappaB- and specificity protein 1-dependent p53 mediated bi-directional regulation of the human manganese superoxide dismutase gene
Shen et al., Sci China C Life Sci 2003 : In addition, SOD/catalase down-regulated the expression of p53 , p21/wafl/cipl and TBARS but up-regulated bcl-2 and increased indirectly the level of NO, NO2-/NO3-, and inhibited DNA fragmentation