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CREB1 — CXCR4
Text-mined interactions from Literome
Fukuda et al., Blood 2005
(Acute Disease...) :
In contrast, prolonged exposure of CD34+ or Ba/F3-Flt3 cells to FL down-regulated
CXCR4 expression,
inhibited CXCL12 mediated phosphorylation of MAPK ( p42/p44 ),
CREB , and Akt, and impaired migration toward CXCL12
Kim et al., Cell Mol Life Sci 2010
(Breast Neoplasms...) :
Furthermore,
CREB3 was shown to bind to the CRE element in the CXCR4 promoter and to
activate the transcription of the
CXCR4 gene by causing dissociation of HDAC3 and subsequently increasing histone acetylation