Gene interactions and pathways from curated databases and text-mining

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BCL2 — PLD6

Text-mined interactions from Literome

Katz et al., Blood 2004 (MAP Kinase Signaling System) : We now show that overexpression of Bcl-xL can prevent mitochondrial phospholipase A2 activation, disruption of mitochondrial potential, and postmitochondrial execution of BCR mediated apoptosis via cathepsin B activation
Yoon et al., Biochem J 2012 : The purpose of the present study was to investigate the role of PLD ( phospholipase D ) in bFGF ( basic fibroblast growth factor ) -induced Bcl-2 expression and to examine whether overexpressed Bcl-2 influences neurite outgrowth in immortalized hippocampal progenitor cells ( H19-7 cells ) ... In conclusion, PLD1 acts as a downstream effector of bFGF/Ras/PI3K/PLC? signalling and regulates Bcl-2 expression through JNK/STAT3, which leads to neurite outgrowth in H19-7 cells