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AKT3 — LIF

Text-mined interactions from Literome

Hiraoka et al., Kobe J Med Sci 2003 (Cardiomyopathies...) : PI 3-kinase-Akt-p70 S6 kinase in hypertrophic responses to leukemia inhibitory factor in cardiac myocytes
Paling et al., J Biol Chem 2004 : Inhibition of PI3Ks reduced basal and LIF stimulated phosphorylation of PKB/Akt , GSK3alpha/beta, and S6 proteins
Lu et al., J Biol Chem 2006 : As shown in mammary gland epithelial cells, expression of the phosphatidylinositol 3-kinase regulatory subunits p50alpha and p55alpha was induced in response to LIF in SOCS3 ( -/- ) MEFs but not in wild-type MEFs, and Akt/protein kinase B activity was substantially reduced in SOCS3 ( -/- ) MEFs
Magni et al., Mol Endocrinol 2007 : Leukemia inhibitory factor induces the chemomigration of immortalized gonadotropin releasing hormone neurons through the independent activation of the Janus kinase/signal transducer and activator of transcription 3, mitogen activated protein kinase/extracellularly regulated kinase 1/2, and phosphatidylinositol 3-kinase/Akt signaling pathways
Wysoczynski et al., Cancer Res 2007 (Neoplasm Metastasis...) : We found that in rhabdomyosarcoma cells, LIF stimulates the following : ( a ) phosphorylation of mitogen activated protein kinase p42/44, AKT , and signal transducers and activators of transcription 3, ( b ) adhesion and chemotaxis, and ( c ) increased resistance to cytostatics
Miyamoto et al., Cell Death Differ 2008 : Furthermore, the association of Akt with HK-II is increased by LIF
Ueki et al., J Neurochem 2008 : Akt was not activated by LIF
Slaets et al., Proteomics 2008 : Leukemia inhibitory factor induces an antiapoptotic response in oligodendrocytes through Akt-phosphorylation and up-regulation of 14-3-3
Ransome et al., Mol Cell Neurosci 2008 : However, while Leukemia Inhibitory Factor (LIF) similarly stimulated phosphorylation of Akt , it had no effect on axonal or dendritic growth, indicating that AKT phosphorylation is necessary but not sufficient for neurite outgrowth in hippocampal neurons
Quaglino et al., BMC cell biology 2009 : In addition, we found that mammary cell stretching triggered involution associated cellular events as Leukemia Inhibitory Factor (LIF) expression induction, STAT3 activation and AKT phosphorylation inhibition
Bürgi et al., Molecular vision 2009 (Retinal Degeneration) : Presence or absence of LIF did not affect AKT ( also known as protein kinase B, PKB ) signaling and had only a mild effect on extracellular regulated kinase (ERK) phosphorylation
Lee et al., J Lipid Res 2010 : However, caveolin-1 siRNA did not influence LIF induced phosphorylation of STAT3 and Akt , and expression of c-Myc
Miyamoto et al., Circ Res 2010 : The ability of PHLPP-1 knockdown to potentiate LIF mediated increases in p-Akt at mitochondria and an accompanying increase in mitochondrial hexokinase-II was demonstrated