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EPHB2 — GRB10
Text-mined interactions from Literome
Mori et al., Mol Cell Endocrinol 2005
:
In spite of these differences, both
FL-Grb10 and the BPS-SH2 fragment
inhibited insulin stimulated phosphorylation of IRS1, IRS2, Akt/PKB, Shc,
ERK1/2 , APS, and c-Cbl to a similar extent
Kebache et al., J Biol Chem 2007
(Adenocarcinoma...) :
Because total Raf-1,
ERK , and Akt kinase activities are not
impaired in the absence of
Grb10 , we propose that this adapter protein creates a subpopulation of Raf-1 with specific anti-apoptotic activity