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SDS — SLC17A5

Text-mined interactions from Literome

Ortolani et al., Vet Hum Toxicol 2003 (Drug-Induced Liver Injury...) : The following changes were significantly recorded in the CL sheep in the weeks or days previous to the hemolytic crisis : higher levels of gammaGT were found on the -28th d increasing slowly but continuously until the hemolytic crisis ; SDH fluctuated during the period presenting higher levels on the -28th, -14th and -7th d ; AST and AF activities increased from the -14th and -7th d respectively ; sharp decreases in the activities of SDH and AF at the hemolytic crisis ; lower feed intake and body weight gain from the -7th d ; and sheep ceased eating concentrates from the -9th d and became anoretic the day before the hemolytic crisis
Wu et al., Biol Pharm Bull 2008 (Drug-Induced Liver Injury) : SDS significantly protected APAP induced hepatotoxicity for SDS improved mouse survival rates better than NAC against a lethal dose of APAP and significantly blocked not only APAP induced increases of AST , ALT, and TNF-alpha but also APAP induced GSH depletion and MDA accumulation