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HSP90AA1 — SMYD2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: SMYD2 — HSP90AA1 (physical association, affinity chromatography technology) Abu-Farha et al., Mol Cell Proteomics 2008*
• IRef Biogrid Interaction: SMYD2 — HSP90AA1 (direct interaction, enzymatic study) Abu-Farha et al., Journal of molecular cell biology 2011*

Text-mined interactions from Literome

Abu-Farha et al., Mol Cell Proteomics 2008 : We demonstrated that the interaction of SMYD2 with HSP90alpha enhances SMYD2 histone methyltransferase activity and specificity for histone H3 at lysine 4 ( H3K4 ) in vitro
Jiang et al., PloS one 2011 : Our results thus provide the first evidence for the intradomain flexibility of the TPR-like CTD, which may be important for the activation of SmyD proteins by Hsp90