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APOB — MMP14
Text-mined interactions from Literome
Rajavashisth et al., J Biol Chem 1999
:
Ox-LDL also
increased MT1-MMP mRNA levels that varied with the duration of exposure and degree of LDL oxidation
Ardans et al., J Leukoc Biol 2002
:
ox-LDL,
LDL , and HDL alone
had no effect on MMP-1,
MMP-9 , or TIMP-1 production
Kume et al., Nihon rinsho. Japanese journal of clinical medicine 2004
(Arteriosclerosis) :
Lectin-like oxidized LDL receptor-1 ( LOX-1 ) is a cell surface receptor for oxidized LDL, which is abundantly expressed in atherosclerotic plaques and is involved in oxidized
LDL induced
MMP production and apoptosis
May et al., Thromb Haemost 2005
(Arteriosclerosis) :
We studied the
effect of
E-LDL on the activation of plasminogen and matrix metalloproteinases ( MMPs ) in monocytes and vascular smooth muscle cells ( VSMCs ) as well as on
MMP activation during cellular interactions ... Together, enzymatical modification of
LDL allows a direct activation of
MMP expression in monocytes and VSMCs, and indirectly promotes the induction of paracrine, cytokine mediated intercellular activation processes
Sugimoto et al., Cardiovasc Res 2009
:
Ox-LDL induced rapid RhoA and Rac1 activation as well as
MT1-MMP activity in cultured human aortic ECs