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MAPK3 — PLG
Text-mined interactions from Literome
Giuliani et al., J Cell Sci 1999
:
Role of endothelial cell
extracellular signal regulated kinase1/2 in urokinase-type
plasminogen activator upregulation and in vitro angiogenesis by fibroblast growth factor-2
Jingjing et al., Angiogenesis 2001
:
CM from 293-VEGF183 cells treated with heparin or
plasmin induced about a twofold increase in cell numbers and
stimulated MAPK phosphorylation in HUVECs as compared with CM from untreated 293-VEGF183 cells or from heparin- or plasmin treated 293 cells containing the vector alone
Simkhovich et al., Cardiovasc Pathol 2003
(Myocardial Ischemia) :
Protective genes included
mitogen activated protein kinase activated protein kinase 3 ( MAPKAPK 3 ), heat shock proteins 70, 27, 22, B-crystalline, vascular endothelial growth factor, inducible nitric oxide synthase and
plasminogen activator inhibitors 1 and 2
Ulfhammer et al., Journal of thrombosis and haemostasis : JTH 2006
(Cardiovascular Diseases...) :
TNF-alpha mediated suppression of tissue type
plasminogen activator expression in vascular endothelial cells is NF-kappaB- and p38
MAPK dependent
Yoshida et al., Blood Coagul Fibrinolysis 2007
(Carcinoma, Small Cell...) :
Urokinase-type plasminogen activator and interleukin-8 are important biological factors in tumor cell regulation ; STI571 may therefore influence many aspects of tumor cell biology through inducing urokinase-type
plasminogen activator and interleukin-8, in which the induction of early growth response-1 expression and
extracellular signal regulated kinase 1/2 phosphorylation might be
involved
Zhang et al., J Immunol 2007
:
Interaction of
plasmin with annexin A2
resulted in the stimulation of ERK1/2 and p38
MAPK , cyclooxygenase-2, and PGE ( 2 ), leading to increased MMP-1 production
Zare et al., J Leukoc Biol 2008
:
In contrast,
Plg production did not require NF-kappaB, was only partly
down-regulated by p38
MAPK inhibitor, and was efficiently inhibited by insulin, indicating a different mechanism for its induction
Tang et al., J Biol Chem 1998
:
The urokinase-type
plasminogen activator receptor
mediates tyrosine phosphorylation of focal adhesion proteins and activation of
mitogen activated protein kinase in cultured endothelial cells