Zhu et al., J Biol Chem 2007
:
We found that Mps1 is involved in turning on Smad signaling by phosphorylating R-Smads
Hirschhorn et al., PloS one 2012
(Ovarian Neoplasms) :
Furthermore, an Mps1 dependent phosphorylation of GFP-Smad3 was also observed upon its over-expression in interphase cells, suggesting a mechanism of negative regulation which counters increases in Smad3 concentration