Gene interactions and pathways from curated databases and text-mining

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GRAP2 — MAP2K1

Text-mined interactions from Literome

Ishikawa et al., J Neurochem 2000 : In addition, the BDNF accelerated apoptosis was inhibited by the addition of SB202190 and SB203580, specific inhibitors of p38 mitogen activated protein kinase ( MAPK ), and U0126, a specific inhibitor of MAPK/ERK kinase 1 , indicating that the activation of both p38 MAPK and ERK is involved in the signaling cascade of the BDNF accelerated, NO donor induced apoptosis
Sharma-Walia et al., J Virol 2005 (Herpesviridae Infections...) : Purified soluble gpK8.1A induced the MEK1/2 dependent ERK1/2 but not ERK5 and p38 mitogen activated protein kinase ( MAPK ) in HMVEC-d and HFF
Lee et al., J Cell Physiol 2006 : TNF-alpha enhanced expression of VCAM-1 protein and mRNA as well as phosphorylation of p42/p44 MAPK, p38 , and JNK were significantly attenuated by inhibitors of MEK1/2 ( U0126 ), p38 ( SB202190 ), and JNK ( SP600125 )
Dolinay et al., PloS one 2008 (Edema...) : We characterize the role of p38 mitogen activated protein kinase/mitogen activated protein kinase kinase-3 and c-Jun-NH ( 2 ) -terminal kinase-1 in ventilator induced lung injury and investigate novel independent mechanisms contributing to lung injury during mechanical ventilation