Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Bock et al., J Biol Chem 2003 : Here we demonstrate that PI3K activation by Reelin requires Src family kinase activity and depends on the Reelin triggered interaction of Dab1 with the PI3K regulatory subunit p85alpha
Arnaud et al., Mol Cell Biol 2003 : We have made use of mouse embryo cortical neuron cultures in which Reelin induces Dab1 tyrosine phosphorylation and Src family kinase activation
Morimura et al., Brain Res 2009 : Reelin regulates radial migration of the projection neurons in the developing cerebral cortex by inducing tyrosine phosphorylation of an intracellular adaptor protein, Disabled-1 (Dab1), through activation of Src family tyrosine kinases (SFKs)
Wei et al., Am J Pathol 2011 : The FAK-Src complex, activated by upstream reelin and integrin ß1, can initiate a cascade of phosphorylation events to trigger multiple intracellular pathways, including mitogen activated protein kinase-extracellular signal regulated kinase and phosphatidylinositol 3-kinase-Akt signaling