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CD40LG — MYC
Text-mined interactions from Literome
Donjerković et al., Cell Growth Differ 1999
(Lymphoma, B-Cell) :
This down-regulation of
c-Myc is
prevented by
CD40L , which rescues cells from anti-IgM induced apoptosis
Daumer et al., J Bone Miner Res 2002
:
Both
v-Myc and c-Myc negatively
regulated transcription from the
TRAP promoter in P388D1 and C3H10T1/2 cells, 90 % and 50 %, respective to cell type and amount of endogenous Myc protein, and delta84/NLS had no effect ... This report provides the first evidence of the specific
regulation of
TRAP at the transcriptional level by
Myc , a transcription factor that is normally expressed at relatively high levels in preosteoclasts and other myelomonocytic cells and suggests that Myc plays an active role in suppressing the transcription of a mature osteoclast selective gene