◀ Back to ATR
ATR — PRKDC
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Intact Interaction:
Complex of 11 proteins
(association, pull down)
Izumi et al., Science signaling 2010
-
IRef Intact Interaction:
Complex of ATR-RUVBL2-TTI2-MTOR-ATM-TELO2-PRKDC-TTI1
(association, tandem affinity purification)
Takai et al., Genes Dev 2010
-
IRef Intact Interaction:
Complex of 11 proteins
(association, tandem affinity purification)
Takai et al., Genes Dev 2010
-
IRef Intact Interaction:
Complex of ATM-TTI1-MTOR-ATR-PRKDC-SMG1
(association, anti tag coimmunoprecipitation)
Hurov et al., Genes Dev 2010
-
IRef Intact Interaction:
Complex of PRKDC-TELO2-ATR
(association, affinity chromatography technology)
Takai et al., Cell 2007
-
IRef Intact Interaction:
Complex of MTOR-ATM-TELO2-ATR-PRKDC-TRRAP
(association, anti bait coimmunoprecipitation)
Takai et al., Cell 2007
Text-mined interactions from Literome
Müller et al., J Cell Biol 2007
:
DNA-PK is activated during replication stress and DNA-PK signaling is
enhanced when
ATR/ATM signaling is abrogated
Gong et al., Mol Cell 2010
:
ATR signaling was abrogated by shRNAs to ATR and TopBP1, but shRNAs to the ATM kinase or
DNA-PKcs did not
affect the telomere damage response