Gene interactions and pathways from curated databases and text-mining

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ICR4 — MMP9

Text-mined interactions from Literome

O-charoenrat et al., Cancer Res 2000 (Carcinoma, Squamous Cell...) : Antagonist ( ICR62 ) or agonist ( ICR9 ) anti-EGFR monoclonal antibodies, respectively, inhibited or potentiated MMP-9 activity and tumor cell invasion induced by all ligands
O-charoenrat et al., Clin Exp Metastasis 1999 (Carcinoma, Squamous Cell...) : A specific anti-EGFR monoclonal antibody ( mAb ICR62 ) inhibited MMP up-regulation, migration and invasion induced by all three ligands, whereas an anti-c-erbB-2 mAb ICR12 inhibited mitogenic and motogenic responses following ligand stimulation but had no effect on MMP expression