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ETS1 — KDR

Pathways - manually collected, often from reviews:

• NCI Pathway Database HIF-2-alpha transcription factor network: ETS1 (ETS1) → VEGFR2 (KDR) (transcription, activates) Elvert et al., J Biol Chem 2003*
  Evidence: mutant phenotype, reporter gene, physical interaction

Text-mined interactions from Literome

Sato et al., Ann N Y Acad Sci 2000 : The KDR/Flt-1 heterodimer and the KDR homodimer mediate the expression of Ets-1 , MMP-1, and Flt-1
Kappel et al., Blood 2000 : c-Ets1 , a transcription factor that is coexpressed with Flk-1 during embryonic development and tumor angiogenesis, activated the Flk-1 promoter via 2 binding sites