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BBS2 — NOS2

Text-mined interactions from Literome

Ramasamy et al., Circulation 2004 (Myocardial Ischemia...) : To investigate whether selective inhibition of NOS2 is cardioprotective, rats were pretreated for 2 days with BBS2 , an inhibitor of NOS2 dimerization, at 15 mg/kg SC. Isolated buffer perfused hearts from treated ( n=9 ) and control ( n=7 ) hearts were subjected to 20 minutes of ischemia followed by 60 minutes of reperfusion ... Pretreatment with BBS2 , a selective inhibitor of NOS2 , improves contractile performance, preserves myocardial ATP, and reduces damage and death of cardiac myocytes during ischemia and reperfusion of isolated buffer perfused rat hearts
Oliveira et al., Shock 2004 (Burns...) : We also tested the hypothesis that BBS-2 , a specific inhibitor of iNOS , would impair NO formation after burn
Enkhbaatar et al., Shock 2006 (Disease Models, Animal...) : Continuous infusion of BBS-2 ( 100 microg/kg/h ), an iNOS inhibitor , was started 1 h after insult
Lange et al., Crit Care Med 2009 (Acute Lung Injury) : Following baseline measurements, the animals were allocated to either sham injured, nontreated controls ( sham ), injured, nontreated controls ( control ), or injured animals treated with continuous infusion of 7-nitroindazole, a specific neuronal nitric oxide synthase inhibitor, during the first 12 hrs postinjury and infusion of BBS-2 , a specific inducible nitric oxide synthase inhibitor , during the next 12 hrs