Gene interactions and pathways from curated databases and text-mining

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FAS — ICAM1

Text-mined interactions from Literome

Inoue et al., Int Arch Allergy Immunol 2001 (Acute Disease...) : Exposure of HUVEC to recombinant human TNF-alpha increased the expression of both ICAM-1 and Fas , but a much lower concentration was required for an effect upon ICAM-1
Choi et al., Neurosci Lett 2003 (Astrocytoma...) : Induction of intercellular adhesion molecule-1 by Fas ligation : proinflammatory roles of Fas in human astroglioma cells ... We demonstrate that Fas ligation induces ICAM-1 expression at the mRNA and protein levels in human astroglioma cells ... Studies using Boc-D-Fmk, a pharmacological inhibitor, show that caspase activation is required for Fas mediated ICAM-1 induction ... These findings suggest that Fas ligation on human glioma cells leads to the induction of ICAM-1 expression, which involves caspase cascade signaling pathways
Papasavvas et al., AIDS 2008 (Chronic Disease...) : We assessed changes in plasma levels of von Willebrand factor, soluble vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 by enzyme linked immunosorbent assay, as well as T-cell activation ( CD8+/CD38+, CD8+/HLA-DR+ and CD3+/CD95+ ) by flow cytometry, in 36 chronically HIV-1 infected patients participating in a randomized study