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CD8A — IL6
Text-mined interactions from Literome
Tscharke et al., Arch Virol 1999
(Disease Models, Animal...) :
The determine which cytokines might be involved in the
CD8 ( + ) cell dependent
response to ganglionic HSV infection, IL-2, IL-4,
IL-6 , IL-10, and IFN-gamma mRNA levels were measured in infected ganglia from immunocompetent and anti-CD8 treated mice
Lee et al., J Interferon Cytokine Res 2000
(Mast-Cell Sarcoma) :
Dose dependent and schedule dependent
effects of
interleukin-12 on antigen-specific
CD8 responses
Borger et al., J Heart Lung Transplant 2002
:
Depletion of CD4+ and/or
CD8+ had no effect on the
IL-6 and IL-8 production induced by the total CD2+ lymphocyte-population
Cao et al., Cell Mol Immunol 2004
(Carcinoma...) :
Global gene expression profiling in
interleukin-12 induced activation of
CD8 ( + ) cytotoxic T lymphocytes against mouse mammary Carcinoma
Liu et al., J Leukoc Biol 2007
:
In this study, we demonstrated that TGF-beta and
IL-6 could
stimulate CD8 ( + ) cells to differentiate into noncytotoxic, IL-17 producing cells in MLC
Gagnon et al., J Immunol 2008
:
We propose that the ability of
IL-6 to
induce TCR independent activation of
CD8 ( + ) T cells in synergy with IL-7 or IL-15 may play an important role in the transition from innate to adaptive immunity
Chaput et al., Gut 2009
(Adenocarcinoma...) :
Finally,
interleukin 6 and TGF beta 1 synergistically
induced the generation of
CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Cash et al., J Rheumatol 2010
(Inflammation...) :
The absence of
IL-6 resulted in significant reduction of infiltrating macrophages in the kidney ( p < 0.05 ), a decrease in renal IgG and C3 deposition, and a reduction of CD4+ and
CD8+ lymphocytes
Marcinkiewicz et al., Folia Histochem Cytobiol 1990
(Dermatitis, Contact...) :
The recent data can be interpreted to show that
IL-6 released by activated macrophages ( APC cells ) in the induction phase of the CS reaction probably
stimulate CD8+ T suppressor cells
Ma et al., Scand J Immunol 2011
(Colonic Neoplasms) :
This study aims to investigate the
role of tumour derived Foxhead box P3 (Foxp3) ( +
) interleukin (IL)-17 ( + ) T cells on suppressing tumour-specific
CD8 ( + ) T cells
Tittarelli et al., Cancer Immunol Immunother 2012
(Melanoma...) :
Antibody blocking of monocyte TLR4 inhibited surface expression, determined by flow cytometry, of the major histocompatibility complex class I, CCR7, CD80, CD83 and CD86 on TAPCells, reduced
interleukin (IL)-6 and tumor necrosis factor -a gene expression evaluated by qRT-PCR, and also
inhibited the TAPCells mediated interferon-? ( IFN-? ) secretion of melanoma-specific
CD8 ( + ) T cells determined by ELISpot ( p < 0.01 )
Höllsberg et al., Proc Natl Acad Sci U S A 1995
:
CD8 T-cell stimulation with the wild-type peptide antigen
led to activation of p56lck kinase activity,
interleukin 2 secretion, cytotoxicity, and clonal expansion