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IGF1 — M6PR
Text-mined interactions from Literome
Damke et al., Biochem J 1992
:
IGF-I , IGF-II and phorbol ester
increased the surface expression of the M6P/IGF-II receptor and of
MPR46 ... IGF-I,
IGF-II and phorbol ester
increased the surface expression of the M6P/IGF-II receptor and of
MPR46
Bach et al., Endocrinology 1995
:
These results suggest that 1 ) IGF-II induced proliferation and differentiation of L6A1 myoblasts are predominantly mediated by the IGF-I receptor ; 2 ) the
IGF-II/mannose 6-phosphate receptor is not required for these actions of IGF-II ; 3 ) nevertheless, the IGF-II/mannose 6-phosphate receptor may be capable of mediating these actions ; and 4 ) IGFBPs secreted by myoblasts
inhibit IGF actions