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IFNB1 — SOAT1
Text-mined interactions from Literome
Novick et al., J Interferon Cytokine Res 2000
:
The 117.7 mAb, representative of this class of receptor nonblocking mAb, induced hyper-tyrosine phosphorylation of IFNAR-2 in the
presence of
IFN-alpha/beta but did not inhibit IFN-alpha/beta induced
Jak-Stat tyrosine phosphorylation and ISGF3 complex formation
Andrejeva et al., J Virol 2002
:
In contrast,
STAT2 was absent from 2f/PIV2-V cells, and
IFN-alpha/beta but not IFN-gamma signaling was
blocked in these cells
Parisien et al., J Virol 2002
:
Results indicate that neither the
IFN-alpha/beta receptor, the tyrosine kinases Jak1 or Tyk2, nor the ISGF3 DNA binding subunit, IFN regulatory factor 9 (IRF9), is
required for
STAT protein degradation induced by either virus
Nguyen et al., Science 2002
(Arenaviridae Infections) :
Here we show that
IFN-alpha/beta activate STAT4 directly (
STAT , signal transducers and activators of transcription ) and that this is required for IFN-gamma production during viral infections of mice, in concert with T cell receptor derived signals
Hu et al., J Leukoc Biol 2008
:
In this study, we analyzed the regulation of
STAT signaling during maturation of human DCs by TNF-alpha and PGE2, which induced maturation of human DCs comparably with LPS but did not
induce detectable
IFN-beta production or Stat1 tyrosine phosphorylation
Schaber et al., Cancer Res 1998
(Breast Neoplasms) :
By analyzing the effect of PRL on
IFN alpha/beta induced tyrosine phosphorylation of
Stat proteins and their binding to IFN regulated genes, we now report that costimulation of PRL receptors did not interfere with IFN alpha/beta signals in several human breast cancer cell lines, including T47D, MCF-7, and BT-20