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EDN1 — TLR3

Text-mined interactions from Literome

Farina et al., Ann Rheum Dis 2011 (Scleroderma, Systemic) : Together these data show that the dsRNA can regulate genes associated with vascular activation, as seen in SSc, that type I IFNs do not mediate these effects, and that EDN1 and ECE1 but not ICAM-1 activation is mediated by TLR3
George et al., Biochem Biophys Res Commun 2012 (Hypertension, Pulmonary) : Using specific TLR ligands, we found that activation of TLRs 3 and 4 resulted in IL-8 release by human pulmonary artery smooth muscle cells but that only TLR3 stimulation resulted in IP10 and endothelin-1 release