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IRF6 — LYZ

Text-mined interactions from Literome

Paulsen et al., Fish Shellfish Immunol 2001 : The rather late increase in lysozyme production induced by beta-glucan and LPS may thus be explained by stimulation of differentiation of the macrophages in culture eventually combined with direct activation of transcription of the lysozyme gene
Regenhard et al., J Leukoc Biol 2001 (Calcium Signaling) : Involvement of PKA, PKC, and Ca2+ in LPS activated expression of the chicken lysozyme gene ... The lysozyme gene is activated in myelomonocytic HD11 cells in response to LPS ... In this study, we described the involvement of LPS activated signal transduction pathways in activation of the lysozyme gene
Paulsen et al., Fish Shellfish Immunol 2003 : In vivo effects of beta-glucan and LPS on regulation of lysozyme activity and mRNA expression in Atlantic salmon ( Salmo salar L. ) ... The present study was undertaken to compare the effects of intraperitoneally injected bacterial lipopolysaccharide (LPS) and yeast beta-glucan on lysozyme activity in Atlantic salmon, and to explore what organ ( s ) are responsible for the increase in plasma lysozyme activity induced by the compounds ... The results indicated that LPS stimulates plasma lysozyme activity at least as efficiently as beta-glucan ... Increased lysozyme activity in response to both beta-glucan and LPS was demonstrated in blood PMN and cells isolated from head kidney and intestine ... Based on previous work and the present results it is suggested that plasma lysozyme induced by LPS and beta-glucan originate from macrophages in the different organs
Tanida et al., J Biochem 1992 : Recent studies by our group suggested that lysozyme has a high affinity for bacterial lipopolysaccharide (LPS) of both the smooth and rough forms, and inhibits various immunomodulatory activities of LPS
Rasool et al., Infect Immun 1992 : The comparison between Brucella LPS and lipid A versus Salmonella LPS revealed that at least 100 times more LPS and 1,000 times more lipid A of the former genus were required to induce significant nitroblue tetrazolium reduction and a corresponding lysozyme release in neutrophils
Chen et al., J Leukoc Biol 1991 (Candidiasis) : On the other hand, LPS suppressed lysozyme activity in M phi from young, but not aging mice
Ohno et al., Carbohydr Res 1991 : The binding of lysozyme (LZM) to bacterial lipopolysaccharide (LPS) inhibited the biological activities of LPS as well as the enzymic activity of LZM
Jarstrand et al., Scand J Infect Dis 1991 : However, when the neutrophils were incubated with LPS together with Intralipid, the LPS induced stimulation of the neutrophil NBT reduction, chemiluminescence and lysozyme release was significantly decreased
Lewis et al., Immunology 1990 : Differential effects of LPS , IFN-gamma and TNF alpha on the secretion of lysozyme by individual human mononuclear phagocytes : relationship to cell maturity
Myrnes et al., Dev Comp Immunol 2013 : LPS induced expression of c-type lysozyme and broad constitutive tissue distribution of g-type lysozyme in salmon is different from findings in other studied fish species
Witham et al., PloS one 2013 : The transcriptional activation of the chicken lysozyme gene ( cLys ) by lipopolysaccharide (LPS) in macrophages is dependent on transcription of a LPS-Inducible Non Coding RNA (LINoCR) triggering eviction of the CCCTC binding factor (CTCF) from a negative regulatory element upstream of the lysozyme transcription start site
Ohno et al., Eur J Biochem 1989 : Both Re-LPS- and lipid-A dependent immunostimulatory activities were readily inhibited by lysozyme in a dose dependent fashion ... These differences were not the result of quantitative differences in LPS binding of lysozyme, or effects of lysozyme on overall binding of LPS to target cells
Weiss et al., Proc Natl Acad Sci U S A 1978 (Leukemia, Experimental...) : Lipopolysaccharides (LPS) from different bacteria induced the appearance of rosettes, lysozyme , and macrophages in some MGI ( + ) D ( + ) clones but did not induce any of these changes in MGI ( + ) D ( - ) clones
Wiernik et al., J Clin Lab Immunol 1986 : The effects of purified Salmonella endotoxin ( LPS ) and of LPS combined with isolated human plasma high density lipoproteins ( HDL ) on oxidative metabolism, measured by nitroblue tetrazolium ( NBT ) -test, and on lysozyme release of human granulocytes have been studied in vitro ... The stimulating effect of LPS on NBT-reduction and lysozyme release was significantly diminished when the cells were incubated with LPS together with HDL
Strunk et al., J Clin Invest 1985 : Using metabolic labeling with [ 35S ] methionine, immunoprecipitation, and SDS-polyacrylamide gel electrophoresis, we examined the effects of LPS on synthesis of C3 by human mononuclear phagocytes as well as synthesis of the second component of complement ( C2 ), factor B, lysozyme , and total protein
Kasukabe et al., Jpn J Cancer Res 1985 (Leukemia, Myeloid...) : Of the agents tested, butyrate, conditioned medium from concanavalin A-stimulated spleen cells, lipopolysaccharide (LPS) and N6,O2-dibutyryl adenosine 3'5'-cyclic-monophosphate ( dbcAMP ) significantly stimulated the lysozyme activity of Mm-A cells, which is one of the most characteristic biochemical markers of monocytes and macrophages
Goethe et al., J Biol Chem 1994 : By transient and stable transfection of the chloramphenicol acetyltransferase (CAT) gene controlled by regulatory elements of the lysozyme gene, we identified a subfragment of the -6.1 kilobase ( kb ) lysozyme enhancer that mediates the LPS induced lysozyme expression ... These results show that the -6.1 kb lysozyme enhancer, in addition to its role in cell type-specific expression, can mediate, by interacting with NF-M, LPS induced expression of the lysozyme gene in chicken myelomonocytic cells
Takada et al., Infect Immun 1994 (Shock, Septic) : We previously showed that lysozyme (LZM) was an LPS binding protein and inhibited various immunomodulating activities of LPS
Tanida et al., Biol Pharm Bull 1993 : Recent studies by our group suggested that lysozyme (LZM) has a high affinity for bacterial lipopolysaccharide (LPS) of both the smooth and rough forms, and inhibits various immunomodulatory activities of LPS
Lei et al., J Biol Chem 1993 : Additional studies have documented that LPS binding to PT may be competitively inhibited by lysozyme but not by polymyxin B. Sequence analysis has allowed identification of a high degree of amino acid sequence similarity between the S2 subunit of PT and hen egg white lysozyme at the N-terminal 80-residue regions
Kurasawa et al., FEMS Immunol Med Microbiol 1996 : We have demonstrated that egg-white lysozyme ( EW-LZM ) bound to lipopolysaccharide (LPS), reduced the lethal toxicity and the biological activity of LPS
Goethe et al., J Leukoc Biol 1997 : C/EBPbeta has been shown to mediate the lipopolysaccharide (LPS) induced expression of the lysozyme gene through enhanced binding to the -6.1-kb lysozyme enhancer
Goethe et al., J Immunol 1998 : However, Northern analyses with lysozyme cDNA and intron sequences revealed that the LPS induced increase in nuclear lysozyme transcripts greatly exceeded the increase in transcription rate