Gene interactions and pathways from curated databases and text-mining

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HLA-DRB1 — IFNB1

Text-mined interactions from Literome

Beyer et al., Glia 2000 : Interferon-beta (IFN-beta) , a substance clinically used in the treatment of the relapsing remitting form of multiple sclerosis, was shown to inhibit the phagocytosis induced upregulation of MHC-class II
Satoh et al., Neurology 2001 (Multiple Sclerosis) : Previously, the authors showed that IFN beta inhibited IFN gamma induced major histocompatibility complex ( MHC) class II expression on astrocytes
Lu et al., J Exp Med 1995 (Fibrosarcoma) : The mechanism of IFN-beta mediated MHC class II inhibition has been unclear
Li et al., Immunopharmacol Immunotoxicol 1998 : Effect of propranolol and IFN-beta on the induction of MHC class II expression and cytokine production by IFN-gamma IN THP-1 human monocytic cells