Gene interactions and pathways from curated databases and text-mining

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NPPA — PTGS2

Text-mined interactions from Literome

Kiemer et al., Endocrinology 2002 : ANP reduces COX-2-protein and -mRNA levels
Kiemer et al., Shock 2002 : No effect of ANP on LPS activated inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 protein levels, iNOS mRNA expression, nitric oxide, and PGE2 production was observed
Bai et al., Peptides 2009 (Hypertension, Renal) : Regulation of ANP secretion from isolated atria by prostaglandins and cyclooxygenase-2 ... The aim of this study was to determine the role of various PGs and COX-2 in the regulation of atrial natriuretic peptide (ANP) secretion ... In hypertrophied rat atria, PGF2alpha induced positive inotropy and ANP secretion were markedly attenuated whereas COX-2 inhibitor stimulated ANP secretion