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MMP2 — NOX4

Text-mined interactions from Literome

Luchtefeld et al., Biochem Biophys Res Commun 2005 (Cardiomyopathies...) : Since reactive oxygen species ( ROS ) induce MMP-2 and angiotensin II (ANG II) enhances NADPH-oxidase dependent ROS formation, we assessed whether ANG II induces MMP-2 in a NADPH-oxidase dependent manner
Li et al., Diabetes 2005 : Overall, these results demonstrate that leptin induced HASMC proliferation and MMP-2 expression through a PKC dependent activation of NAD ( P ) H oxidase with subsequent activation of the ERK1/2/NF-kappaB pathways and that therapeutic metformin concentrations effectively inhibit these biological effects
Spallarossa et al., Cardiovasc Res 2006 (MAP Kinase Signaling System) : Inhibition of NAD ( P ) H oxidase attenuates the increase in MMP-2 , but augments the doxorubicin induced increase in MMP-9
Cook-Mills et al., Cell Mol Biol Incl Cyto Enzymol 2006 : The endothelial cell NADPH oxidase and endothelial cell MMP activities are required for VCAM-1 dependent lymphocyte migration as determined by scavenging of ROS, by pharmacologic or antisense inhibition of NADPH oxidase and by pharmacologic inhibition of endothelial cell MMPs
Diebold et al., Mol Biol Cell 2011 : NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II