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STX1A — TNF
Text-mined interactions from Literome
Zhang et al., J Lab Clin Med 2001
(Escherichia coli Infections) :
The results showed that anisodamine significantly suppressed
Stx1 induced
tumor necrosis factor-alpha (TNF-alpha) , interleukin-1beta (IL-1beta), and IL-8 production ... Reverse transcriptase-polymerase chain reaction ( RT-PCR ) showed that anisodamine suppressed
Stx1 mediated
TNF-alpha mRNA expression
Stricklett et al., J Infect Dis 2002
:
TNF , both alone and in combination with IL-1,
increased Stx-1 toxicity, Gb3 content, and
Stx-1 binding
Lee et al., Infect Immun 2005
(Leukemia, Myeloid) :
Here, we show that
Stx1 induces apoptosis in the undifferentiated myelogenous leukemia cell line THP-1 in the absence of
tumor necrosis factor alpha (TNF-alpha) or death receptor ( TNF receptor or Fas ) expression
Hughes et al., Kidney Int 1998
(Hemolytic-Uremic Syndrome) :
Stx-1 greatly
increased TNF release and mRNA levels while CHX, at concentrations that produced similar inhibition of protein synthesis, had no effect on TNF production