Gene interactions and pathways from curated databases and text-mining

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FLT3 — HSP90AA1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Minami et al., Leukemia 2002 (Cell Transformation, Neoplastic...) : These findings imply that targeting of Hsp90 will facilitate the development of anti-TDFLT3 therapy, and that Hsp90 is closely involved in the oncogenic activation of FLT3
Reikvam et al., Br J Haematol 2012 (Leukemia, Myeloid, Acute...) : FLT3 ligation further increased the levels of HSP90 and its co-chaperone HSP70