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RELA — VHL
Text-mined interactions from Literome
An et al., Oncogene 2005
(Carcinoma, Renal Cell...) :
Using isogenic paired cell lines with and without expression of wtVHL, we have confirmed that
VHL expression
reduces constitutive
NF-kappaB activity
An et al., Mol Cell Biol 2005
(Kidney Neoplasms) :
Recently,
VHL loss was shown to
activate nuclear factor kappa B (NF-kappaB) , a family of transcription factors that promotes tumor growth
Pantuck et al., Cancer Res 2010
(Carcinoma, Renal Cell...) :
Based on earlier evidence that
VHL loss can
activate NF-kappaB , a known mediator of EMT, we tested whether NF-kappaB contributed to VHL mediated effects on EMT