Gene interactions and pathways from curated databases and text-mining

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IGF1 — TRIM63

Text-mined interactions from Literome

Waddell et al., Am J Physiol Endocrinol Metab 2008 (Muscular Atrophy) : Finally, chromatin immunoprecipitation analysis reveals that both GR and FOXO1 bind to the endogenous MuRF1 promoter in C ( 2 ) C ( 12 ) myotubes, and IGF-I inhibition of DEX induced MuRF1 expression correlates with the loss of FOXO1 binding
Glass et al., Curr Opin Clin Nutr Metab Care 2010 (Cachexia...) : The insulin-like growth factor-1 can block the transcriptional upregulation of MuRF1 and MAFbx via the phosphatidylinositol-3 kinase/Akt/Foxo pathway
López-Menduiña et al., Am J Physiol Regul Integr Comp Physiol 2010 (Arthritis, Experimental...) : IGF-I attenuated the arthritis induced increase in atrogin-1 and MuRF1 expression in the gastrocnemius, whereas it did not modify the expression of these genes in the soleus muscle