Gene interactions and pathways from curated databases and text-mining

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EPO — TIMP1

Text-mined interactions from Literome

Kadri et al., Cell Growth Differ 2000 (MAP Kinase Signaling System) : Inhibition of the mitogen activated protein kinase pathway by the specific inhibitors PD98059 and U0126 and of phosphatidylinositol 3-kinase by LY294002, strongly inhibited Epo induced TIMP-1 expression and secretion
Kadri et al., Mol Cell Biol 2005 : We report here that erythropoietin regulates the transcription of the TIMP-1 gene upon binding to its receptor in erythroid cells by triggering the activation of phosphatidylinositol 3-kinase (PI3K)/Akt