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IL1A — SOAT1
Text-mined interactions from Literome
Weber et al., Am J Physiol Endocrinol Metab 2004
:
In addition, these ligands impair
IL-1 induced NF-kappaB and MAPK as well as IFN-gamma stimulated signal transducer and activator of transcription (
STAT ) 1 activation in beta-cells
Suzuki et al., Cytokine 2010
(MAP Kinase Signaling System) :
Finally, IL-6+sIL-6R induced
IL-1RI expression was
inhibited by a
STAT pathway inhibitor, but not a MAPK pathway inhibitor
Kondo et al., Arch Biochem Biophys 2013
:
SP600125 remarkably suppressed the IL-1 induced phosphorylation of both I?B and NF-?B, whereas SP600125 failed to affect the
IL-1 induced phosphorylation of AMPK,
STAT3 or Src
Reddy et al., Proc Soc Exp Biol Med 1998
:
These data reveal that collagenase gene expression can be regulated by the impairment of
IL-1 stimulated NF-kappaB,
STAT3 , and AP-1 activities, and can highlight a possible molecular mechanism for the anti-inflammatory effects of glucocorticoids