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IL2 — SELL
Text-mined interactions from Literome
Frey et al., J Exp Med 1992
:
We have examined
induction of
endothelial-leukocyte adhesion molecule 1 expression by human umbilical vein endothelial cells,
interleukin 6 secretion by U373 astrocytoma cells, and cytotoxicity of bovine endothelial cells
Picker et al., J Immunol 1993
:
Differential regulation of L-selectin can also be demonstrated in vitro by the activation of virgin T cells in the presence of specific cytokines --
IL-2 induces
L-selectin down-regulation, whereas IL-6 and particularly TGF-beta 1 promote L-selectin up-regulation
Deisher et al., Life Sci 1993
(Second Messenger Systems) :
Surface protein expression of vascular cell adhesion molecule-1, endothelial
leukocyte adhesion molecule-1 , or intercellular adhesion molecule-1, which is
induced by tumor necrosis factor,
interleukin-1 , and lipopolysaccharide, was not induced by pentoxyfilline, a phosphodiesterase inhibitor, nor by dibutyryl cyclic adenosine monophosphate
Baumgartner-Parzer et al., Diabetologia 1995
:
Stimulation of confluent HUVECs, kept in 30 vs 5 mmol/l glucose for 13 +/- 1 days, with 20 U/ml
interleukin-1 for 24 h ( ICAM-1 ) and 4 h ( endothelial leukocyte adhesion molecule 1 )
resulted in reduced ICAM-1 ( 84.8 +/- 27.0 %, p < 0.05 ) and endothelial
leukocyte adhesion molecule-1 ( 87.6 +/- 22.4 %, p < 0.05 ) expression vs control cells, while that of PECAM ( t : 24 h ) and vascular cell adhesion molecule-1 ( t : 16 h ) remained unchanged
Frey et al., J Immunol 1998
:
NK activation by PMA,
IL-2 , IL-15, or TGF-beta
down-regulated L-selectin on the CD56bright subset, while increased L-selectin levels were observed in both the CD56bright and CD56dim NK subsets in response to IL-12, IL-10, or IFN-alpha